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Secnidazole

Cat. No.:YN251222

  • CAS No. :3366-95-8

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    • 产品名称: Secnidazole
      CAS No.: 3366-95-8
      Chemical Name: α,2-dimethyl-5-nitro-1H-imidazole-1-ethanol
      Synonyms:塞克硝唑; RP-14539; PM-185184
      分子量:185.18
      分子式:C₇H₁₁N₃O₃
      SMILES:OC(C)CN1C([N+]([O-])=O)=CN=C1C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Secnidazole (RP-14539;PM-185184) 是一种具有口服活性唑类抗生素 (antibiotic),其半衰期比甲硝唑 (HY-B0318) 更长。Secnidazole 阴道病相关细菌有抑制作用,有潜力用于细菌性阴道病的研究。
      IC50和靶点:
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    • Nagata, N., Mariott, D., Harkenss, J., et al.Current treatment options for Dientamoeba fragilis infectionsInt. J. Parasitol. Drugs Drug Resist.2,204-215(2012)

      Jokipii, L., and Jokipii, A.M.Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis groupAntimicrob. Agents Chemother.28(4),561-564(1985)

      Almirall, P., Escobedo, A.A., Ayala, I., et al.Mebendazole compared with secnidazole in the treatment of adult giardiasis: a randomised, no-inferiority, open clinical trialJ. Parasitol. Res.2011,636857(2011)

      Silva, F.M., Eisig, J.N., Chehter, E.Z., et al.Low efficacy of an ultra-short term, once-daily dose triple therapy with omeprazole, azithromycin, and secnidazole for Helicobacter pylori eradication in peptic ulcerRev. Hosp. Clin. Fac. Med. Sao Paulo57(1),9-14(2002)

      Omrani, G., Rastegar-Lari, A., and Khamseh, M.Effect of single dose of secnidazole in treatment of intestinal amoebiasisJ. Pak. Med. Assoc.4596),159(1995)

      De backer, E., Dubreuil, L., Brauman, M., et al.In vitro activity of secnidazole against Atopobium vaginae, an anaerobic pathogen involved in bacterial vaginosisClin. Microbiol. Infect.16(5),470-472(2010)

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