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Amodiaquine dihydrochloride dihydrate

Cat. No.:YN251290

  • CAS No. :6398-98-7

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    • 产品名称: Amodiaquine dihydrochloride dihydrate
      CAS No.: 6398-98-7
      Chemical Name: 4-[(7-Chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]phenol Dihydrochloride; Dihydrate; 4-[(7-chloro-4-quinolyl)amino]-α-(diethylamino)-cresol Dihydrochloride, Dihydrate; Amodiaquin Dihydrochloride Dihydrate; Amodiaquine Dihydrochloride Dihydrate
      Synonyms:阿莫地喹盐酸盐; Amodiaquin dihydrochloride dihydrate
      分子量:464.81
      分子式:C₂₀H₂₂ClN₃O . ₂H₂O . ₂HCl
      SMILES:OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CN(CC)CC.Cl.Cl.O.O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Amodiaquine dihydrochloride dihydrate (Amodiaquin dihydrochloride dihydrate) 是一种4-氨基喹啉类抗疟剂,是一种有效的具有口服活性的组胺 N-甲基转移酶 (histamine N-methyltransferase) 抑制剂。Amodiaquine dihydrochloride dihydrate 也是一种Nurr1激动剂,可特异性结合Nurr1的配体结合域,EC50为 ~20 μM。抗炎作用。
      IC50和靶点:
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      Solvent & Solubility:
    • Natarajan, L., et al.: Arzneim.-Forsch., 22, 1230 (1972), Kracmer, J., et al.: Pharmazie, 29, 773 (1974), Ahmad, I., et al.: Anal. Profiles Drug Subs., 21, 43 (1992),

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