Tuberostemonine
Cat. No.：YN251476
CAS No. ：6879-01-2
| 产品名称: | Tuberostemonine |
| CAS No.: | 6879-01-2 |
| Chemical Name: | (2S,7aR,8R,8aS,11S,11aS,11bR,11cR)-(8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one |
| Synonyms: | 对叶百部碱 |
| 分子量: | 375.50 |
| 分子式: | C₂₂H₃₃NO₄ |
| SMILES: | [H][C@@]([C@]1([H])[C@@]23[H])(CCCCN1[C@]([H])([C@@]4([H])OC([C@@H](C)C4)=O)C3)[C@@H](CC)[C@]([C@]2([H])[C@@H]5C)([H])OC5=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tuberostemonine 是一种生物碱，是一种抗疟疾剂 (antimalarial) ，可靶向恶性疟原虫铁氧还蛋白-NADP+还原酶 (pfFNR)。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Brem, B., Seger, C., Pacher, T., et al.Feeding deterrence and contact toxicity of Stemona alkaloids-a source of potent natural insecticidesJ. Agric. Food Chem.50(22),6383-6388(2002)
Zhou, X., Leung, P.H.H., Li, N., et al.Oral absorption and antitussive activity of tuberostemonine alkaloids from the roots of Stemona tuberosaPlanta Med.75(6),575-580(2009)
Jung, K.-H., Beak, H., Park, S., et al.The therapeutic effects of tuberostemonine against cigarette smoke-induced acute lung inflammation in miceEur. J. Pharmacol.774,80-86(2016)
