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Artemether

Cat. No.:YN251484

  • CAS No. :71963-77-4

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    • 产品名称: Artemether
      CAS No.: 71963-77-4
      Chemical Name: (3R,5aS,6R,8aS,9R,10S,12R,12aR)-decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
      Synonyms:蒿甲醚; Dihydroqinghaosu methyl ether; Dihydroartemisinin methyl ether; SM224
      分子量:298.37
      分子式:C₁₆H₂₆O₅
      SMILES:C[C@H]1[C@@H](OC)O[C@@]2([H])[C@]34[C@@]([C@H](C)CC[C@]41[H])([H])CC[C@@](O2)(C)OO3
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Artemether是抗疟疾化合物,可作用于恶性疟疾的耐药株。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Xiao, S.H., and Catto, B.A.In vitro and in vivo studies of the effect of artemether on Schistosoma mansoniAntimicrob. Agents Chemother.33(9),1557-1562(1989)

      Pillai, D.R., Lau, R., Khairnar, K., et al.Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infectionsMalar. J.11,131(2012)

      Shmuklarsky, M.J., Klayman, D.L., Milhous, W.K., et al.Comparison of β-artemether and β-arteether against malaria parasites in vitro and in vivoAm. J. Trop. Med. Hyg.48(3),377-384(1993)

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