Quassin
Cat. No.：YN251561
| 产品名称: | Quassin |
| CAS No.: | 76-78-8 |
| Chemical Name: | 2,12-dimethoxy-picrasa-2,12-diene-1,11,16-trione |
| Synonyms: | Nigakilactone D |
| 分子量: | 388.45 |
| 分子式: | C₂₂H₂₈O₆ |
| SMILES: | C[C@@H]([C@@]1(C[C@]2(OC(C[C@]([C@]2([C@]3([C@@]41C)[H])C)(C(C)=C(OC)C3=O)[H])=O)[H])[H])C=C(OC)C4=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Quassin (Nigakilactone D) 是一种从Quassia amara的茎皮提取物中提取的生物活性三萜。Quassin 抑制P. falciparum，IC50为 0.15 μM。Quassin 具有可逆的抗生育能力，抗雌激素和抗疟原虫活性。 |
| IC50和靶点: | |
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Mishra, K., Chakraborty, D., Pal, A., et al.Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisininExp. Parasitol.124(4),421-427(2010)
Daido, M., Fukamiya, N., Okano, M., et al.Antifeedant and insecticidal activity of quassinoids against diamondback moth (Plutella xylostella)Biosci. Biotechnol. Biochem.57(2),2440246(1993)
He, C., Wang, Y., Yang, T., et al.Quassinoids with insecticidal activity against Diaphorina citri Kuwayama and neuroprotective activities from Picrasma quassioidesJ. Agric. Food. Chem.68(1),117-127(2020)
