Febrifugine
Cat. No.：YN251597
| 产品名称: | Febrifugine |
| CAS No.: | 24159-07-7 |
| Chemical Name: | 3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone |
| Synonyms: | 常山乙素 |
| 分子量: | 301.34 |
| 分子式: | C₁₆H₁₉N₃O₃ |
| SMILES: | O=C1N(CC(C[C@H]2NCCC[C@@H]2O)=O)C=NC3=C1C=CC=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Febrifugine 是存在于常山的根和叶中的一种喹唑啉酮类生物碱，具有抗疟活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Koepfli, J.B., Mead, J.F., and Brockman, J.A., Jr.An alkaloid with high antimalarial activity from Dichroa febrifugaJ. Am. Chem. Soc.69(7),1837(1947)
McLaughlin, N.P., Evans, P., and Pines, M.The chemistry and biology of febrifugine and halofuginoneBioorg. Med. Chem.22(7),1993-2004(2014)
Murata, K., Takano, F., Fushiya, S., et al.Potentiation by febrifugine of host defense in mice against Plasmodium berghei NK65Biochem. Pharmacol.58(10),1593-1601(1999)
