Biotin-PEG2-C4-alkyne
Cat. No.：YN1440013
CAS No. ：1011268-28-2
| 产品名称: | Biotin-PEG2-C4-alkyne |
| CAS No.: | 1011268-28-2 |
| Chemical Name: | (3aS,4S,6aR)-hexahydro-2-oxo-N-[2-[2-[2-[(1-oxo-5-hexyn-1-yl)amino]ethoxy]ethoxy]ethyl]-1H-thieno[3,4-d]imidazole-4-pentanamide |
| Synonyms: | |
| 分子量: | 468.61 |
| 分子式: | C₂₂H₃₆N₄O₅S |
| SMILES: | O=C(NCCOCCOCCNC(CCCC#C)=O)CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Biotin-PEG2-C4-alkyne 是一种基于 PEG 结构的PROTAC linker，可用于 PROTAC 的合成。 |
| IC50和靶点: | |
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McClatchy, D.B., Ma, Y., Liu, C., et al.Pulsed azidohomoalanine labeling in mammals (PALM) detects changes in liver-specific LKB1 knockout miceJ. Proteome Res.14(11),4815-4822(2015)
Wu, P., Lu, M.-x., Cui, X.-t., et al.A high-throughput-compatible assay to measure the degradation of endogenous Huntingtin proteinsActa Pharmacol. Sin.37(10),1307-1314(2016)
Zayas, J., Annoual, M., Das, J.K., et al.Strain promoted click chemistry of 2- or 8-azidopurine and 5-azidopyrimidine nucleosides and 8-azidoadenosine triphosphate with cyclooctynes. Application to living cell fluorescent imagingBioconjug. Chem.26(8),1519-1532(2015)
Leonard, S.E., Reddie, K.G., and Carroll, K.S.Mining the thiol proteome for sulfenic acid modifications reveals new targets for oxidation in cellsACS Chem. Biol.4(9),783-799(2009)
