GNF-6231
Cat. No.：YN450006
CAS No. ：1243245-18-2
规格
价格(RMB)
库存
| 产品名称: | GNF-6231 |
| CAS No.: | 1243245-18-2 |
| Chemical Name: | N-[5-(4-Acetyl-1-piperazinyl)-2-pyridinyl]-2'-fluoro-3-methyl[2,4'-bipyridine]-5-acetamide |
| Synonyms: | |
| 分子量: | 448.49 |
| 分子式: | C₂₄H₂₅FN₆O₂ |
| SMILES: | O=C(NC1=NC=C(N2CCN(C(C)=O)CC2)C=C1)CC3=CN=C(C4=CC(F)=NC=C4)C(C)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | GNF-6231是一个强的，有选择性的，能够口服的Porcupine抑制剂能够阻止Wnt信号通路。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Cheng, D., et al.: PCT Int. Appl. (2010), WO 2010101849 A1 20100910
Cheng, D., et al.: ACS Med. Chem. Lett., 7, 676 (2016)
Che, J., et al.: PCT Int. Appl. (2014), WO 2014141038 A2 20140918
