IWP L6
Cat. No.：YN450113
CAS No. ：1427782-89-5
规格
价格(RMB)
库存
| 产品名称: | IWP L6 |
| CAS No.: | 1427782-89-5 |
| Chemical Name: | N-(5-phenyl-2-pyridinyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Synonyms: | Porcn Inhibitor III |
| 分子量: | 472.58 |
| 分子式: | C₂₅H₂₀N₄O₂S₂ |
| SMILES: | O=C(NC1=NC=C(C2=CC=CC=C2)C=C1)CSC3=NC(CCS4)=C4C(N3C5=CC=CC=C5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IWP L6 (Porcn Inhibitor III) 是高活性Porcn抑制剂，EC50为 0.5 nM。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Gao, X., and Hannoush, R.N.Single-cell imaging of Wnt palmitoylation by the acyltransferase porcupineNat. Chem. Biol.10(10),61-68(2014)
Proffitt, K.D., Madan, B., Ke, Z., et al.Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancerCancer Res.73(2),502-507(2013)
Wang, X., Moon, J., Dodge, M.E., et al.The development of highly potent inhibitors for porcupineJ. Med. Chem.56(6),2700-2704(2013)
