ETC-159
Cat. No.：YN450127
CAS No. ：1638250-96-0
规格
价格(RMB)
库存
| 产品名称: | ETC-159 |
| CAS No.: | 1638250-96-0 |
| Chemical Name: | 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-N-(6-phenyl-3-pyridazinyl)-7H-purine-7-acetamide |
| Synonyms: | ETC-1922159 |
| 分子量: | 391.38 |
| 分子式: | C₁₉H₁₇N₇O₃ |
| SMILES: | O=C(NC1=CC=C(C2=CC=CC=C2)N=N1)CN3C=NC4=C3C(N(C)C(N4C)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ETC-159 (ETC-1922159) 是有效的，具有口服活性的PORCN抑制剂。抑制β-catenin报告基因活性的IC50值为2.9 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Madan, B., Ke, Z., Harmston, N., et al.Wnt addiction of genetically defined cancers reversed by PORCN inhibitionOncogene35(17),2197-2207(2016)
