Ac-FLTD-CMK
Cat. No.:YN330106
产品名称: | Ac-FLTD-CMK |
CAS No.: | 2376255-48-8 |
Chemical Name: | |
Synonyms: | CID 155906572;Ac-FLTD-CMK |
分子量: | 569.05 |
分子式: | C₂₆H₃₇ClN₄O₈ |
SMILES: | ClCC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@@H](NC(C)=O)CC1=CC=CC=C1)=O)=O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ac-FLTD-CMK 是胃泌素 D (GSDMD) 衍生的抑制剂,是炎症性caspases的特异性抑制剂。Ac-FLTD-CMK 对caspases-1(IC50为 46.7 nM),caspases-4(IC50为 1.49 μM),caspases-5(IC50为 329 nM) 和caspases-11均有效,但对凋亡相关的 caspase-3 无效。 |
IC50和靶点: | [{name:"Caspase-1:46.7 nM (IC50)"},{name: "Caspase-4:1.49 μM (IC50)"},{name: "Caspase-5:329 nM (IC50)'}, 'Caspase-11'] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |