Polyphyllin VI
Cat. No.：YN330586
| 产品名称: | Polyphyllin VI |
| CAS No.: | 55916-51-3 |
| Chemical Name: | (3β,25R)-17-hydroxyspirost-5-en-3-yl 2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-Glucopyranoside; 17-Hydroxyparis V; Paris VI; Paris Saponin VI; Pennogenin; 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside; Olygonatoside B3 ;Saponin Tb |
| Synonyms: | 重楼皂苷VI |
| 分子量: | 738.90 |
| 分子式: | C₃₉H₆₂O₁₃ |
| SMILES: | O[C@]1([C@@]2([H])O[C@]3(CC[C@@H](C)CO3)[C@H]1C)[C@]([C@@]4([H])C2)(CC[C@@]5([H])[C@@]4([H])CC=C6[C@@]5(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]8O)([H])[C@@H]8O)C6)C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Polyphyllin VI，一种主要分离自传统药用植物Paris polyphylla的活性皂甙，具有抗癌活性。Polyphyllin VI 诱导 G2/M 细胞周期停滞并引发细胞凋亡。Polyphyllin VI 通过诱导非小细胞肺癌中的 ROS/NF-κB/NLRP3/GSDMD 信号轴来诱导 caspase-1 介导的细胞焦亡 (pyroptosis)。 |
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Yin, X. et al.: Biomed. Chrom., 27, 343 (2013)
Jiang, H. et al.: Mol. Med. Rep., 9, 2265 (2014)
Cheng, Z. et al.: J. Ethnopharmacol., 120, 129 (2008)
