RI-2
Cat. No.:YN290407
产品名称: | RI-2 |
CAS No.: | 1417162-36-7 |
Chemical Name: | 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
Synonyms: | RI2,RI 2 |
分子量: | 433.28 |
分子式: | C₂₁H₁₈Cl₂N₂O₄ |
SMILES: | O=C(C(C1=CC=C(OC)C=C1)=C2N3CCOCC3)N(C4=CC=C(Cl)C(Cl)=C4)C2=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RI-2 是一种可逆的RAD51抑制剂,IC50值为 44.17 μM,能够特异性地抑制人体细胞中的同源重组修复。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Budke, B., Kalin, J.H., Pawlowski, M., et al.An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivityJ. Med. Chem.56(1),254-263(2013)