SPP-86
Cat. No.：YN440137
CAS No. ：1357349-91-7
规格
价格(RMB)
库存
| 产品名称: | SPP-86 |
| CAS No.: | 1357349-91-7 |
| Chemical Name: | |
| Synonyms: | SPP 86;1-Isopropyl-3-(phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;BDBM50388620;SPP86, >=98% (HPLC);3-(2-Phenylethynyl)-1-propan-2-ylpyrazolo[3,4-d]pyrimidin-4-amine;SPP-86 |
| 分子量: | 277.32 |
| 分子式: | C₁₆H₁₅N₅ |
| SMILES: | CC(C)N1C2=NC=NC(N)=C2C(C#CC3=CC=CC=C3)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SPP-86 是一种选择性的RET 酪氨酸激酶的有效抑制剂，其IC50值为 8 nM。SPP-86 抑制 MCF7 细胞中 RET 诱导激活的 PI3K/Akt 和 MAPK 信号通路，也能抑制 RET 诱导的 ERα 磷酸化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
