PK68
Cat. No.：YN270199
CAS No. ：2173556-69-7
| 产品名称: | PK68 |
| CAS No.: | 2173556-69-7 |
| Chemical Name: | |
| Synonyms: | RIPK1 inhibitor PK68 |
| 分子量: | 424.52 |
| 分子式: | C₂₂H₂₄N₄O₃S |
| SMILES: | O=C(OC1CCCCC1)NC2=CC(C3=CC=C4N=C(NC(C)=O)SC4=C3)=CN=C2C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PK68 是一种高效选择性的 II 型RIPK1抑制剂，IC50值约为 90 nM，可抑制 RIPK1 依赖性的 necroptosis。PK68 能有效改善 TNF 诱导的全身炎症反应综合征，在炎症性疾病和癌症转移研究方面的应用具有很大潜力。 |
| IC50和靶点: | [{name:"RIPK1:90 nM (IC50)"},{name: "RIPK1:23 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
