Necrostatin 2 racemate
Cat. No.：YN270287
| 产品名称: | Necrostatin 2 racemate |
| CAS No.: | 852391-15-2 |
| Chemical Name: | 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methyl-2,4-imidazolidinedione |
| Synonyms: | Necrostatin 1S; Nec-1S; 7-Cl-O-Nec1 |
| 分子量: | 277.71 |
| 分子式: | C₁₃H₁₂ClN₃O₂ |
| SMILES: | ClC1=C2C(C(CC3C(N(C)C(N3)=O)=O)=CN2)=CC=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Necrostatin 2 racemate (Nec-1S)，是一种稳定型 Nec-1 (HY-15760 )，Necrostatin 2 racemate 是一种有效且特异性的RIPK1抑制剂，但缺乏 IDO 靶向作用。 |
| IC50和靶点: | |
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Takahashi, N., Duprez, L., Grootjans, S., et al.Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease modelsCell Death Dis.3(11),e437(2012)
Huang, Z., Epperly, M., Watkins, S.C., et al.Necrostatin-1 rescues mice from lethal irradiationBiochim. Biophys. Acta1862(4),850-856(2016)
