Y-27632
Cat. No.：YN450010
CAS No. ：146986-50-7
规格
价格(RMB)
库存
| 产品名称: | Y-27632 |
| CAS No.: | 146986-50-7 |
| Chemical Name: | |
| Synonyms: | Y-27632 DIHYDROCHLORIDE;ROCK INHIBITOR;(R)-(+)-TRANS-N-(4-PYRIDYL)-4-(1-AMINOETHYL)-CYCLOHEXANECARBOXAMIDE 2HCL;(R)-(+)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL)CYCLOHEXANECARBOXAMIDE DIHYDROCHLORIDE;(+)-R-TRANS-4-(AMINOETHYL)-N-(4-PYRIDYL)-CYCLOHEXANECARBOXAM |
| 分子量: | 247.34 |
| 分子式: | C₁₄H₂₁N₃O |
| SMILES: | O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Y-27632 是一种ATP竞争性的ROCK-I和ROCK-II抑制剂，Ki分别为 220 nM 和 300 nM，Y-27632 通过上皮-间充质过渡样调节引发人的诱导多能干细胞 (hIPSCs) 选择性地分化为间胚层谱系。 |
| IC50和靶点: | [{name:"ROCK-I:220 nM (Ki)"},{name: "ROCK-II:300 nM (Ki)"},{name: "PKN:3.1 μM (Ki)"},{name: "Citron kinase:5.3 μM (Ki)"},{name: "PKCα:73 μM (Ki)"},{name: "PKA:25 μM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
