Chroman 1
Cat. No.：YN450096
CAS No. ：1273579-40-0
规格
价格(RMB)
库存
| 产品名称: | Chroman 1 |
| CAS No.: | 1273579-40-0 |
| Chemical Name: | (3S)-N-[2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide |
| Synonyms: | |
| 分子量: | 436.50 |
| 分子式: | C₂₄H₂₈N₄O₄ |
| SMILES: | O=C([C@@H]1COC2=CC=C(OC)C=C2C1)NC3=CC=C(C4=CNN=C4)C=C3OCCN(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Chroman 1 dihydrochloride 是一种高效的ROCK2抑制剂，IC50值 1 nM。Chroman 1 dihydrochloride 对MRCK也有抑制作用，其IC50值为 150 nM。 |
| IC50和靶点: | [{name:"ROCK2:1 pM (IC50)"},{name: "ROCK1:52 pM (IC50)"},{name: "MRCK:150 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Chen, Y.T., Vojkovsky, T., Fang, X., et al.Asymmetric synthesis of potent chroman-based Rho kinase (ROCK-II) inhibitorsMed. Chem. Commun.2(1),73-75(2011)
