SAR407899 hydrochloride
Cat. No.:YN450107
产品名称: | SAR407899 hydrochloride |
CAS No.: | 923262-96-8 |
Chemical Name: | |
Synonyms: | 6-(哌啶-4-氧基)异喹啉-1(2H)-酮盐酸盐 |
分子量: | 280.75 |
分子式: | C₁₄H₁₇ClN₂O₂ |
SMILES: | O=C(NC=C1)C(C1=C2)=CC=C2OC3CCNCC3.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SAR407899 hydrochloride 是一种选择性的,有效的,ATP 竞争性的ROCK抑制剂,对ROCK-2的IC50值为 135 nM,对人和大鼠ROCK-2的Ki值分别为 36 nM 和 41 nM。 |
IC50和靶点: | [{name:"ROCK-2:102 nM (IC50)"},{name: "ROCK-1:276 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |