RAF265
Cat. No.：YN350021
CAS No. ：927880-90-8
| 产品名称: | RAF265 |
| CAS No.: | 927880-90-8 |
| Chemical Name: | 1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine |
| Synonyms: | CHIR-265 |
| 分子量: | 518.41 |
| 分子式: | C₂₄H₁₆F₆N₆O |
| SMILES: | FC(F)(C1=CN=C(N1)C2=NC=CC(OC3=CC=C4N(C(NC5=CC=C(C(F)(F)F)C=C5)=NC4=C3)C)=C2)F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RAF265 是一种有效的RAF/VEGFR2抑制剂。 |
| IC50和靶点: | |
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Huang, T., Karsy, M., Zhuge, J., et al.B-Raf and the inhibitors: From bench to bedsideJ. Hematol. Oncol.6,1-9(2013)
Su, Y., Vilgelm, A.E., Kelley, M.C., et al.RAF265 inhibits the growth of advanced human melanoma tumorsClin. Cancer Res.18(8),2184-2198(2012)
