LUT014
Cat. No.:YN350074
CAS No. :2274819-46-2
产品名称: | LUT014 |
CAS No.: | 2274819-46-2 |
Chemical Name: | |
Synonyms: | LUT014;ZB1544;N5-(3-(9H-purin-6-yl)pyridin-2-yl)-6-methyl-N1-(3-(trifluoromethoxy)phenyl)isoquinoline-1,5-diamine;6-Methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]-1-N-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamin |
分子量: | 528.49 |
分子式: | C₂₇H₁₉F₃N₈O |
SMILES: | FC(F)(F)OC1=CC(NC2=NC=CC3=C2C=CC(C)=C3NC4=NC=CC=C4C5=C6N=CNC6=NC=N5)=CC=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LUT014 是一种B-Raf抑制剂,IC50值为 11.7 nM,被开发用于减少与 EGFR 抑制剂相关限制剂量的痤疮样病变的研究。详细信息请参考专利文献 WO 2019026065A2。 |
IC50和靶点: | [{name:"B-Raf:11.7 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |