B-Raf IN 1
Cat. No.：YN350182
| 产品名称: | B-Raf IN 1 |
| CAS No.: | 950736-05-7 |
| Chemical Name: | N-[3-[3-[4-[(dimethylamino)methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3-(trifluoromethyl)-benzamide |
| Synonyms: | B-RafIN1;BenzaMide, N-[3-[3-[4-[(diMethylaMino)Methyl]phenyl]pyrazolo[1,5-a]pyriMidin-7-yl]phenyl]-3-(trifluoroMethyl)-;B-Raf IN 1 |
| 分子量: | 515.53 |
| 分子式: | C₂₉H₂₄F₃N₅O |
| SMILES: | O=C(NC1=CC=CC(C2=CC=NC3=C(C4=CC=C(CN(C)C)C=C4)C=NN23)=C1)C5=CC=CC(C(F)(F)F)=C5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | B-Raf IN 1 是一种有效的选择性B-Raf抑制剂， IC50为 24 nM。 |
| IC50和靶点: | [{name:"B-Raf:24 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
Berger, D.M., Torres, N., Dutia, M., et al.Non-hinge-binding pyrazolo[1,5-α]pyrimidines as potent B-Raf kinase inhibitorsBioorg. Med. Chem. Lett.19(23),6519-6523(2009)
