LJH685
Cat. No.：YN350202
CAS No. ：1627710-50-2
| 产品名称: | LJH685 |
| CAS No.: | 1627710-50-2 |
| Chemical Name: | 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-phenol |
| Synonyms: | LJH685 |
| 分子量: | 381.42 |
| 分子式: | C₂₂H₂₁F₂N₃O |
| SMILES: | OC1=C(F)C=C(C2=C(C3=CC=C(N4CCN(C)CC4)C=C3)C=CN=C2)C=C1F |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LJH685 是一种有效的选择性RSK抑制剂, 抑制 RSK1/2/3 生物活性,IC50为 6、5、4 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Aronchik, I., Appleton, B.A., Basham, S.E., et al.Novel potent and selective inhibitors of p90 ribosomal S6 kinase reveal the heterogeneity of RSK function in MAPK-driven cancersMol. Cancer Res.12(5),803-812(2014)
