TH1217
Cat. No.：YN250511
CAS No. ：1862212-48-3
| 产品名称: | TH1217 |
| CAS No.: | 1862212-48-3 |
| Chemical Name: | |
| Synonyms: | ZINC1775962367 |
| 分子量: | 491.09 |
| 分子式: | C₂₀H₁₇BCl₂N₄O₆ |
| SMILES: | CC1=NC2=C(C(Cl)=C(Cl)C=C2N1CC3=CC=C(C=C3)[B-]45OC(C[N+]4(C)CC(O5)=O)=O)[N+]([O-])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TH1217 (ZINC1775962367) 是一种有效的、选择性的dCTPase pyrophosphatase 1 (dCTPase)抑制剂，IC50值为 47 nM。TH1217 可增强胞苷类似物在白血病细胞中的细胞毒性作用。TH1217 还可以调节 SARS-Cov-2 相互作用体，因此它具有抗 COVID-19 的活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
