ML188
Cat. No.：YN250520
| 产品名称: | ML188 |
| CAS No.: | 1417700-13-0 |
| Chemical Name: | (αR)-N-(1,1-dimethylethyl)-α-[[4-(1,1-dimethylethyl)phenyl](2-furanylcarbonyl)amino]-3-pyridineacetamide |
| Synonyms: | ML188; ML-188; ML 188; |
| 分子量: | 433.54 |
| 分子式: | C₂₆H₃₁N₃O₃ |
| SMILES: | O=C(NC(C)(C)C)[C@@H](C1=CN=CC=C1)N(C(C=C2)=CC=C2C(C)(C)C)C(C3=CC=CO3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ML188，一种探针，也是一种选择性非共价 SARS-CoV3CLpro抑制剂，IC50为 1.5 μM。具有抗病毒活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Jacobs, J., Grum-Tokars, V., Zhou, Y., et al.Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL proteaseJ. Med. Chem.56(2),534-546(2013)
