PLpro inhibitor
Cat. No.：YN250746
| 产品名称: | PLpro inhibitor |
| CAS No.: | 1093070-14-4 |
| Chemical Name: | 5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-benzamide |
| Synonyms: | 5-(乙酰氨基)-2-甲基-N-[(1R)-1-(1-萘基)乙基]苯甲酰胺 |
| 分子量: | 346.42 |
| 分子式: | C₂₂H₂₂N₂O₂ |
| SMILES: | O=C(C1=CC(NC(C)=O)=CC=C1C)N[C@H](C)C2=C(C=CC=C3)C3=CC=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PLpro inhibitor 是一种papain-like protease (PLpro)抑制剂，IC50为 2.6 µM。PLpro inhibitor 还以IC50为 5.0 µM 和EC50为 21.0 µM 来抑制SARS-CoV-2 PLpro。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Ratia, K., Pegan, S., Takayama, J., et al.A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replicationProc. Natl. Acad. Sci. USA105(42),16119-16124(2008)
