Cu(II)GTSM
Cat. No.：YN380405
CAS No. ：68341-14-0
| 产品名称: | Cu(II)GTSM |
| CAS No.: | 68341-14-0 |
| Chemical Name: | (SP-4-2)-[[2,2′-(1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato-κN2,κS]](2-)]-copper |
| Synonyms: | |
| 分子量: | 293.86204 |
| 分子式: | C6H10CuN6S2 |
| SMILES: | CNC1=N[N]2=CC=[N]3[Cu+2]2([S-]1)[S-]C(NC)=N3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cu(II)GTSM 是一种细胞通透性铜复合物，可显著抑制GSK3β。Cu(II)GTSM 抑制Amyloid-β寡聚体(AβOs)，降低tau磷酸化。Cu(II)GTSM 也降低了Amyloid-β三聚体的丰度。Cu(II)GTSM 可以被作为一种潜在的抗癌和抗菌剂。 |
| IC50和靶点: | |
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Xu, C., Xiao, Z., Wang, J., et al.Discovery of a potent glutathione peroxidase 4 inhibitor as a selective ferroptosis inducerJ. Med. Chem.64(18),13312-13326(2023)
Torres, J.B., Andreozzi, E.M., Dunn, J.T., et al.PET imaging of copper trafficking in a mouse model of alzheimer diseaseJ. Nucl. Med.57(1),109-114(2016)
