SNIPER(ABL)-033
Cat. No.:YN430060
产品名称: | SNIPER(ABL)-033 |
CAS No.: | 2222354-18-7 |
Chemical Name: | |
Synonyms: | |
分子量: | 1211.42 |
分子式: | C₆₁H₇₃F₃N₁₀O₉S₂ |
SMILES: | CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCOC6=CC(C(C7=CSC([C@H]8N(C([C@H](C9CCCCC9)NC([C@H](C)NC)=O)=O)CCC8)=N7)=O)=CC=C6)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SNIPER(ABL)-033,由 HG-7-85-01 (ABL 抑制剂) 通过 linker 与 LCL161 衍生物 (cIAP1 配体) 组合而成,可有效降解BCR-ABL蛋白,DC50为 0.3 μM。 |
IC50和靶点: | |
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Clinical Trial: | |
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