Escitalopram oxalate
Cat. No.：YN380097
CAS No. ：219861-08-2
| 产品名称: | Escitalopram oxalate |
| CAS No.: | 219861-08-2 |
| Chemical Name: | (1S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile-D4 Ethanedioate; Escitalopram-D4 Oxalate; (S)-(+)-Citalopram-D4 Oxalate; Cipralex-D4 Oxalate; (S)-1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl-2,3,5,6-d4)-1,3-dih |
| Synonyms: | 依他普仑草酸盐; (S)-Citalopram oxalate; (S)-(+)-Citalopram oxalate |
| 分子量: | 414.43 |
| 分子式: | C₂₂H₂₃FN₂O₅ |
| SMILES: | FC1=CC=C([C@@]2(CCCN(C)C)C(C=CC(C#N)=C3)=C3CO2)C=C1.O=C(O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Escitalopram ((S)-Citalopram) oxalate 是外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂(SSRI)，Ki为 0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。Escitalopram oxalate 对多巴胺转运体 (DAT) 和去甲肾上腺素转运体 (NET) 均有选择性。Escitalopram oxalate 是研究抑郁症的抗抑郁药。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Christensen, A.V., et al.: Eur. J. Pharmacol., 41, 153 (1977), Keller, M.B., et al.: J. Clin. Psychiatry, 61, 896 (2000), Von Moltke, L.L., et al.: Drug Metab. Dispos., 29, 1102 (2001)
