Milnacipran hydrochloride
Cat. No.：YN380165
CAS No. ：101152-94-7
| 产品名称: | Milnacipran hydrochloride |
| CAS No.: | 101152-94-7 |
| Chemical Name: | (1R,2S)-rel-2-(aminomethyl)-N,N-diethyl-1-phenyl-cyclopropanecarboxamide, monohydrochloride |
| Synonyms: | 盐酸米那普仑 |
| 分子量: | 282.81 |
| 分子式: | C₁₅H₂₃ClN₂O |
| SMILES: | O=C([C@@]1(C2=CC=CC=C2)[C@@H](CN)C1)N(CC)CC.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Milnacipran是5-羟色胺-去甲肾上腺素重吸收抑制剂（SNRI），可用于纤维肌痛。 |
| IC50和靶点: | |
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Chen, C., Dyck, B., Fleck, B.A., et al.Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitorsBioorg. Med. Chem.18(4),1346-1349(2008)
Mochizuki, D., Tsujita, R., Yamada, S., et al.Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in ratsPsychopharmacology (Berl)162(3),323-332(2002)
Ueta, K., Suzuki, T., Uchida, I., et al.In vitro inhibition of recombinant ligand-gated ion channels by high concentrations of milnacipranPsychopharmacology (Berl)175(2),241-246(2004)
Suzuki, T., Ueta, K., Tamagaki, S., et al.Antiallodynic and antihyperalgesic effect of milnacipran in mice with spinal nerve ligationAnesth. Analg.106(4),1309-1315(2008)
