Sertraline hydrochloride
Cat. No.：YN380167
| 产品名称: | Sertraline hydrochloride |
| CAS No.: | 79559-97-0 |
| Chemical Name: | (1S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine, monohydrochloride |
| Synonyms: | 盐酸舍曲林 |
| 分子量: | 342.69 |
| 分子式: | C₁₇H₁₈Cl₃N |
| SMILES: | CN[C@H]1CC[C@@H](C2=CC=C(Cl)C(Cl)=C2)C3=C1C=CC=C3.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sertraline hydrochloride 是一种选择性 5- 羟色胺再吸收抑制剂 (SSRI) 类的抗抑郁剂。Sertraline hydrochloride 用于研究多种疾病，例如重度抑郁症和强迫症。 |
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Welch, W.M., Kraska, A.R., Sarges, R., et al.Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralinsJ. Med. Chem.27(11),1508-1515(1984)
Koe, B.K., Weissman, A., Welch, W.M., et al.Sertraline, 1S,4S-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthylamine, a new uptake inhibitor with selectivity for serotoninJ. Pharmacol. Exp. Ther.226(3),686-700(1983)
Carpinteiro, A., Edwards, M.J., Hoffmann, M., et al.Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cellsCell Rep. Med.1(8),100142(2020)
