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Citalopram hydrobromide

Cat. No.:YN380201

  • CAS No. :59729-32-7

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    • 产品名称: Citalopram hydrobromide
      CAS No.: 59729-32-7
      Chemical Name: 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile, monohydrobromide
      Synonyms:Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr
      分子量:405.30
      分子式:C₂₀H₂₂BrFN₂O
      SMILES:N#CC1=CC2=C(C(C3=CC=C(F)C=C3)(CCCN(C)C)OC2)C=C1.[H]Br
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Citalopram hydrobromide ((±)-Citalopram hydrobromide) 是选择性的血清素再摄取抑制剂 (SSRI) 类的抗抑郁试剂, 用于抑郁症的研究。
      IC50和靶点:
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    • Millan, M.J., Gobert, A., Rivet, J.-M., et al.Mirtazapine enhances frontocortical dopaminergic and corticolimbic adrenergic, but not serotonergic, transmission by blockade of α2-adrenergic and serotonin2C receptors: A comparison with citalopramEur. J. Neurosci.12(3),1079-1095(2000)

      Boothman, L.J., Mitchell, S.N., and Sharp, T.Investigation of the SSRI augmentation properties of 5-HT2 receptor antagonists using in vivo microdialysisNeuropharmacology50(6),726-732(2006)

      Bymaster, F.P., Zhang, W., Carter, P.A., et al.Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortexPsychopharmacology (Berl)160(4),353-361(2002)

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