Cinchonidine
Cat. No.:YN380222
产品名称: | Cinchonidine |
CAS No.: | 485-71-2 |
Chemical Name: | (8α,9R)-Cinchonan-9-ol; (-)-Cinchonidine; (8S,9R)-Cinchonidine; (8α,9R)-Cinchonan-9-ol; Cinchovatine; NSC 5364; α-Quinidine; |
Synonyms: | α-Quinidine |
分子量: | 294.39 |
分子式: | C₁₉H₂₂N₂O |
SMILES: | C=C[C@H]1C[N@](CC[C@H]1C2)[C@]2([H])[C@H](O)C3=CC=NC4=CC=CC=C34 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cinchonidine (α-Quinidine) 是在金鸡纳和角蒿中发现的金鸡纳生物碱。 Cinchonidine (α-Quinidine) 是用于有机化学中不对称合成的砌块。是血清素转运蛋白 (SERT)的弱抑制剂,对于dSERT,hSERT,hSERT I172M,hSERT S438T,hSERT Y95F的Ki分别为330,4.2,36,196,15 μM。有抗疟活性.。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Litchfield, J., et al.: J. Pharm. Exp. Ther., 96, 99