Salermide
Cat. No.：YN310037
CAS No. ：1105698-15-4
| 产品名称: | Salermide |
| CAS No.: | 1105698-15-4 |
| Chemical Name: | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
| Synonyms: | |
| 分子量: | 394.47 |
| 分子式: | C₂₆H₂₂N₂O₂ |
| SMILES: | O=C(NC1=CC=CC(/N=C/C2=C3C=CC=CC3=CC=C2O)=C1)C(C)C4=CC=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Salermide是Sirt1andSirt2的抑制剂，可引起强效的癌症特异性的凋亡性细胞死亡。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Yamamoto, H., Schoonjans, K., and Auwerx, J.Sirtuin functions in health and diseaseMol. Endocrinol.21(8),1745-1755(2007)
Milne, J.C., and Denu, J.M.The sirtuin family: Therapeutic targets to treat diseases of agingCurr. Opin. Chem. Biol.12(1),11-17(2008)
Lara, E., Mai, A., Calvanese, V., et al.Salermide, a sirtuin inhibitor with a strong cancer-specific proapoptotic effectOncogene28(6),781-791(2008)
