Thiomyristoyl
Cat. No.:YN310040
CAS No. :1429749-41-6
产品名称: | Thiomyristoyl |
CAS No.: | 1429749-41-6 |
Chemical Name: | N-[(1S)-1-[(phenylamino)carbonyl]-5-[(1-thioxotetradecyl)amino]pentyl]-carbamic acid, phenylmethyl ester |
Synonyms: | TM |
分子量: | 581.85 |
分子式: | C₃₄H₅₁N₃O₃S |
SMILES: | O=C(OCC1=CC=CC=C1)N[C@H](C(NC2=CC=CC=C2)=O)CCCCNC(CCCCCCCCCCCCC)=S |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Thiomyristoyl是高效特异性的SIRT2抑制剂,IC50值为28 nM。 |
IC50和靶点: | [{name:"SIRT2:28 nM (IC50)"},{name: "SIRT1:98 μM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Jing, H., Hu, J., He, B., et al.A SIRT2-selective inhibitor promotes c-Myc oncoprotein degradation and exhibits broad anticancer activityCancer Cell29(3),297-310(2016)