PROTAC Sirt2 Degrader-1
Cat. No.：YN310066
| 产品名称: | PROTAC Sirt2 Degrader-1 |
| CAS No.: | 2098487-75-1 |
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| 分子量: | 852.94 |
| 分子式: | C₄₀H₄₀N₁₀O₈S₂ |
| SMILES: | O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCCCN4C=C(COC5=CC(CC6=CN=C(NC(CSC7=NC(C)=CC(C)=N7)=O)S6)=CC=C5)N=N4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PROTAC Sirt2 Degrader-1 是一种基于 SirReal 的PROTAC，为Sirt2的降解剂，由一个高效、同种型选择性的Sirt2抑制剂，一个连接物和 thalidomide (E3 泛素化连接酶的配体) 组成。PROTAC Sirt2 Degrader-1 对 Sirt2 的IC50值为 0.25 μM，而对 Sirt1/Sirt3 (IC50>100 μM) 无作用。 |
| IC50和靶点: | [{name:"SIRT2:0.25 μM (IC50)"}] |
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