3-TYP
Cat. No.:YN310091
CAS No. :120241-79-4
产品名称: | 3-TYP |
CAS No.: | 120241-79-4 |
Chemical Name: | 3-(1H-1,2,3-triazol-5-yl)-pyridine |
Synonyms: | 3-(1H-1,2,3-triazol-4-yl) pyridine |
分子量: | 146.15 |
分子式: | C₇H₆N₄ |
SMILES: | C1(C2=CN=NN2)=CC=CN=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 3-TYP 是一种选择性的SIRT3抑制剂,IC50值为 16 nM, 比对 SIRT1 和 SIRT2 的选择性强,IC50值分别为 88 nM 和 92 nM。 |
IC50和靶点: | [{name:"SIRT3:16 nM (IC50)"},{name: "SIRT1:88 nM (IC50)"},{name: "SIRT2:92 nM (IC50)"}] |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Galli, U., Mesenzani, O., Coppo, C., et al.Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2Eur. J. Med. Chem.55,58-66(2012)