JFD00244
Cat. No.:YN310100
产品名称: | JFD00244 |
CAS No.: | 96969-83-4 |
Chemical Name: | 1,4-bis[[2-(4-hydroxyphenyl)ethyl]amino]-9,10-anthracenedione |
Synonyms: | |
分子量: | 478.54 |
分子式: | C₃₀H₂₆N₂O₄ |
SMILES: | O=C1C2=C(C=CC=C2)C(C3=C(NCCC4=CC=C(O)C=C4)C=CC(NCCC5=CC=C(O)C=C5)=C13)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | JFD00244 是一种sirtuin 2(SIRT2) 抑制剂。抗肿瘤作用。 |
IC50和靶点: | |
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Clinical Trial: | |
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Kiviranta, P.H., Leppänen, J., Kyrylenko, S., et al.N,N'-Bisbenzylidenebenzene-1,4-diamines and N,N'-bisbenzylidenenaphthalene-1,4-diamines as sirtuin type 2 (SIRT2) inhibitorsJ. Med. Chem.49(26),7907-7911(2006)
Sunami, Y., Araki, M., Hironaka, Y., et al.Inhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cellsPLoS One8(2),57633(2013)