Nicotinamide riboside
Cat. No.：YN310158
| 产品名称: | Nicotinamide riboside |
| CAS No.: | 1341-23-7 |
| Chemical Name: | 3-(aminocarbonyl)-1-β-D-ribofuranosyl-pyridinium |
| Synonyms: | 烟酰胺核糖 |
| 分子量: | 255.25 |
| 分子式: | C₁₁H₁₅N₂O₅ |
| SMILES: | NC(C1=C[N+]([C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)=CC=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nicotinamide riboside 是具有口服活性的 NAD+的前体，可以增加 NAD+水平并激活SIRT1和SIRT3。Nicotinamide riboside 是维生素 B3 (烟酸) 的来源，可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。Nicotinamide riboside 可以减少阿尔茨海默氏病转基因小鼠模型中的认知退化。 |
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Chi, Y., and Sauve, A.A.Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotectionCurr. Opin. Clin. Nutr. Metab. Care15(6),657-661(2013)
Cantó, C., Houtkooper, R.H., Pirinen, E., et al.The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesityCell Metab.15(6),838-847(2012)
Gong, B., Pan, Y., Vempati, P., et al.Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse modelsNeurobiol. Aging34(6),1581-1588(2013)
