SRT 1460
Cat. No.:YN310171
CAS No. :925432-73-1
产品名称: | SRT 1460 |
CAS No.: | 925432-73-1 |
Chemical Name: | |
Synonyms: | SRT1460,3,4,5-三甲氧基-N-(2-(3-(哌嗪-1-基甲基)咪唑并[2,1-B]噻唑-6-基)苯基)苯甲酰胺 |
分子量: | 507.60 |
分子式: | C₂₆H₂₉N₅O₄S |
SMILES: | O=C(NC1=CC=CC=C1C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=CC(OC)=C(OC)C(OC)=C5 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SRT 1460 是一种有效的Sirtuin-1 (SIRT1)激动剂,其EC1.5值为 2.9 μM。与对 SIRT2 和 SIRT3 (EC1.5>300 μM) 相比,SRT 1460 对 SIRT1 有很好的选择性,并且比白藜芦醇和相近 sirtuin 同系物更为有效。 |
IC50和靶点: | [{name:"SIRT1:2.9 μM (EC1.5)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |