Inauhzin
Cat. No.：YN310285
CAS No. ：309271-94-1
| 产品名称: | Inauhzin |
| CAS No.: | 309271-94-1 |
| Chemical Name: | 1-(10H-phenothiazin-10-yl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)-1-butanone |
| Synonyms: | INZ |
| 分子量: | 469.58 |
| 分子式: | C₂₅H₁₉N₅OS₂ |
| SMILES: | CCC(SC1=NN=C2C(NC3=C2C=CC=C3)=N1)C(N4C5=C(C=CC=C5)SC6=CC=CC=C46)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Inauhzin 是SirT1/IMPDH2的双重抑制剂，同时为p53的激活剂，可用于癌症研究。 |
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Zhang, Q., Zeng, S.X., Zhang, Y., et al.A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53EMBO Mol. Med.4(4),298-312(2012)
Zhang, Y., Zhang, Q., Zeng, S.X., et al.Inauhzin and Nutlin3 synergistically activate p53 and suppress tumor growthCancer Biol. Ther.13(10),915-924(2012)
