Resveratrol
Cat. No.：YN310294
| 产品名称: | Resveratrol |
| CAS No.: | 501-36-0 |
| Chemical Name: | 5-[(1E)-2-(4-hydroxyphenyl)ethenyl]-1,3-benzenediol |
| Synonyms: | 白藜芦醇; trans |
| 分子量: | 228.24 |
| 分子式: | C₁₄H₁₂O₃ |
| SMILES: | OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Resveratrol (trans-Resveratrol; SRT501) 是一种天然多酚，具有抗氧化，抗炎，保护心脏和抗癌的特性。 它的靶点广泛，如mTOR、JAK、β-amyloid、Adenylyl cyclase、IKKβ、DNA polymerase。Resveratrol 也是一种特异性的SIRT1活化剂。Resveratrol 是有效的孕烷 X 受体 (PXR) 抑制剂。Resveratrol 是一种Nrf2激活剂，在小鼠模型中可以改善衰老相关的进行性肾损伤。 |
| IC50和靶点: | [{name:"Adenylyl cyclase:0.8 nM (IC50)"},{name: "IKKβ:1 μM (IC50)"},{name: "DNA polymerase α:3.3 μM (IC50)"},{name: "DNA polymerase δ:5 μM (IC50)'}, 'Autophagy', 'Mitophagy', 'Sirtuin'] |
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Jang, M., Cai, L., Udeani, G.O., et al.Cancer chemopreventive activity of resveratrol, a natural product derived from grapesScience275(5297),218-220(1997)
Pirola, L., and Fröjdö, S.Resveratrol: One molecule, many targetsIUMBM Life60(5),323-332(2008)
Borra, M.T., Smith, B.C., and Denu, J.M.Mechanism of human SIRT1 activation by resveratrolJ. Biol. Chem.280(17),17187-17195(2005)
Docherty, J.J., Fu, M.M., Hah, J.M., et al.Effect of resveratrol on herpes simplex virus vaginal infection in the mouseAntiviral Res.67(3),155-162(2005)
