SRT 2183
Cat. No.:YN310330
产品名称: | SRT 2183 |
CAS No.: | 1001908-89-9 |
Chemical Name: | |
Synonyms: | SRT2183 |
分子量: | 468.57 |
分子式: | C₂₇H₂₄N₄O₂S |
SMILES: | O=C(NC1=C(C2=CN3C(SC=C3CN4CC[C@@H](O)C4)=N2)C=CC=C1)C(C=C5)=CC6=C5C=CC=C6 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | SRT 2183 是一种选择性Sirtuin-1 (SIRT1)激活剂,其EC1.5值为 0.36 μM。SRT 2183 诱导生长停滞和凋亡,同时伴随 STAT3 和 NF-κB 去乙酰化,并降低 c-Myc 蛋白水平。 |
IC50和靶点: | [{name:"SIRT1:0.36 μM (EC1.5)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |