LEQ506
Cat. No.:YN450124
产品名称: | LEQ506 |
CAS No.: | 1204975-42-7 |
Chemical Name: | 5-[(2R)-4-[4,5-Dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-2-pyrazinemethanol; NVP LEQ 506 |
Synonyms: | NPV LEQ 506 |
分子量: | 432.56 |
分子式: | C₂₅H₃₂N₆O |
SMILES: | OC(C)(C)C1=NC=C(N2[C@H](C)CN(C3=NN=C(CC4=CC=CC=C4)C(C)=C3C)CC2)N=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LEQ506 是第二代 smoothened (smo) 抑制剂,在人类和小鼠中的IC50值分别为 2 和 4 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Peukert S. et al.: ChemMedChem. 2013 Aug
8(8):1261-5.