Src Inhibitor 1
Cat. No.:YN440026
产品名称: | Src Inhibitor 1 |
CAS No.: | 179248-59-0 |
Chemical Name: | 6,7-dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
Synonyms: | Src Kinase Inhibitor 1; Src-l1 |
分子量: | 373.40 |
分子式: | C₂₂H₁₉N₃O₃ |
SMILES: | COC1=CC2=NC=NC(NC3=CC=C(OC4=CC=CC=C4)C=C3)=C2C=C1OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Src Inhibitor 1是高效选择性的双位点Src酪氨酸激酶抑制剂,对Src和Lck的IC50值分别为44 nM和88 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Tian, G., Cory, M., Smith, A.A., et al.Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolinesBiochemistry40(24),7084-7091(2001)
Bain, J., Plater, L., Elliot, M., et al.The selectivity of protein kinase inhibitors: A further updateBiochem. J.408(3),297-315(2007)