PP2
Cat. No.:YN440292
产品名称: | PP2 |
CAS No.: | 172889-27-9 |
Chemical Name: | 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Synonyms: | AGL 1879 |
分子量: | 301.77 |
分子式: | C₁₅H₁₆ClN₅ |
SMILES: | NC1=C2C(N(C(C)(C)C)N=C2C3=CC=C(Cl)C=C3)=NC=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PP2 是可逆,ATP 竞争性的Src家族抑制剂,抑制Lck和Fyn的IC50分别为 4 和 5 nM。 |
IC50和靶点: | |
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Solvent & Solubility: |
Hanke, J.H., Gardner, J.P., Dow, R.L., et al.Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activationJ. Biol. Chem.271(2),695-701(1996)