Tolimidone
Cat. No.：YN440412
CAS No. ：41964-07-2
规格
价格(RMB)
库存
| 产品名称: | Tolimidone |
| CAS No.: | 41964-07-2 |
| Chemical Name: | 5-(3-methylphenoxy)-2(1H)-pyrimidinone |
| Synonyms: | MLR-1023 |
| 分子量: | 202.21 |
| 分子式: | C₁₁H₁₀N₂O₂ |
| SMILES: | O=C1N=CC(OC2=CC=CC(C)=C2)=CN1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tolimidone 是一个有效且有选择性的Lyn kinase变构激活剂，其EC50值为 63 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Saporito, M.S., Ochman, A.R., Lipinski, C.A., et al.MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro that improves glucose tolerance in vivoJ. Pharmacol. Exp. Ther.342(1),15-22(2012)
Ochman, A.R., Lipinski, C.A., Handler, J.A., et al.The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetesJ. Pharmacol. Exp. Ther.342(1),23-32(2012)
