LQZ-7I
Cat. No.:YN270255
CAS No. :195822-23-2
产品名称: | LQZ-7I |
CAS No.: | 195822-23-2 |
Chemical Name: | N2,N3-bis(4-fluorophenyl)-2,3-quinoxalinediamine |
Synonyms: | |
分子量: | 348.35 |
分子式: | C₂₀H₁₄F₂N₄ |
SMILES: | FC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC4=CC=C(F)C=C4)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LQZ-7I 是一种靶向survivin的抑制剂。LQZ-7I 抑制生存素二聚化。LQZ-7I 口服有效抑制异种移植肿瘤生长并诱导肿瘤中生存素的损失。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Peery, R., Kyei-Baffour, K., Dong, Z., et al.Synthesis and identification of a novel lead targeting survivin dimerization for proteasome-dependent degradationJ. Med. Chem.63(13),7243-7251(2020)