R406
Cat. No.：YN440191
CAS No. ：841290-81-1
规格
价格(RMB)
库存
| 产品名称: | R406 |
| CAS No.: | 841290-81-1 |
| Chemical Name: | 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one Monobenzenesulfonate; Tamatinib; |
| Synonyms: | R-406 besylate |
| 分子量: | 628.63 |
| 分子式: | C₂₈H₂₉FN₆O₈S |
| SMILES: | COC1=CC(NC2=NC(NC3=NC(N4)=C(C=C3)OC(C)(C)C4=O)=C(C=N2)F)=CC(OC)=C1OC.OS(C5=CC=CC=C5)(=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | R406 是一种ATP竞争性的Syk抑制剂，Ki为 30 nM，有效抑制 Syk 激酶活性，IC50为 41 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Borge, M. et al.: J. Immunol., 193, 3165 (2014)
Kimura, Y. et al.: J. Biol. Chem., 289, 31565 (2014)
