Fostamatinib Disodium
Cat. No.：YN440244
CAS No. ：1025687-58-4
规格
价格(RMB)
库存
| 产品名称: | Fostamatinib Disodium |
| CAS No.: | 1025687-58-4 |
| Chemical Name: | 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one, disodium salt |
| Synonyms: | 福他替尼二钠盐; R788(Disodium) |
| 分子量: | 624.42 |
| 分子式: | C₂₃H₂₄FN₆Na₂O₉P |
| SMILES: | COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O[Na])(O[Na])=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fostamatinib Disodium (R788 Disodium) 是活性代谢物R406的原药，是Syk抑制剂，IC50为41 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Singh, R., Masuda, E.S., and Payan, D.G.Discovery and development of spleen tyrosine kinase (SYK) inhibitorsJ. Med. Chem.55(8),3614-3643(2012)
